Prenatal maternal psychosocial stress and offspring’s asthma and allergic disease: a systematic review and meta-analysis
Published on: 19th January 2018
Published in 2018
Pub Med ID: 29331049
Authors: Catherine Flanigan,
Bronwyn K Brew,
Bright I Nwaru
ViewPrenatal maternal stress may influence offspring’s atopic risk through sustained cortisol secretion resulting from activation of the hypothalamic-pituitary-axis (HPA), leading to Th2-biased cell differentiation in the fetus. We undertook a systematic review and meta-analysis investigating the relationship between prenatal maternal psychosocial stress and risk of asthma and allergy in the offspring.