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Best Nootropics: Effective Brain Supplements & Cognitive Enhancers

Best Nootropics: Effective Brain Supplements & Cognitive Enhancers

By Kire Stojkovski M.D
Editor akhila Published 02 May 2024
Time to read 22 min

Ever wished you could boost your brain power and well-being with a simple supplement? You’re not alone. These substances, boasting claims to sharpen memory, ignite creativity, dial in focus, and elevate mood, are the silent allies in the search for a healthy brain boost.

With so many options at your fingertips, how do you pinpoint the one that will turn the key to your cognitive potential? Today’s your lucky day because we’re diving deep into the nootropic world to get the best just for you.

We’re not just talking about any options; we’re zeroing in on the crème de la crème, starting with TakeThesis, a nootropic blend that’s been turning heads.

Best Nootropic Supplements in 2024

Embarking on a journey through the brain-boosting universe, we’ve meticulously selected top-tier nootropic supplements designed to elevate your mental prowess.

Now, let’s break it down—we’re talking key features, standout ingredients, and pricing, all laid out so you can call the shots with confidence.

Remember, it’s not just about popping pills; it’s about making strategic decisions that align with your lifestyle and cognitive aspirations. 

1. TakeThesis – Best Nootropics Overall


  • Offers comprehensive cognitive support
  • Choice of four formulas in the Starter Pack
  • Supports energy, focus, and motivation
  • Well-balanced formulation


  • Higher price point compared to some alternatives

Who Is Thesis Best For?

Thesis is best if you’re seeking a well-rounded nootropic blend to help you remember better or learn tasks faster. Its balanced formula provides comprehensive cognitive support, making it ideal if you’re looking to enhance energy, focus, and motivation throughout the day.

Thesis Benefits

Thesis offers a range of nootropic blends and lets you choose their focus points, from increased energy, improved focus, and enhanced motivation to better memory. The combination of ingredients creates a synergy that supports various aspects of cognitive function.


  • It’s best to take Thesis in the morning on an empty stomach.
  • Take one formula for six days in a row to see how you react.
  • Take a one-day break and move on to the next formula in your starter pack.
  • See which blends work best for you and choose them for your next order, using them according to your preferences.


Thesis incorporates a blend of powerful ingredients such as:

  • Bacopa monnieri: improves memory [1]
  • L-theanine: induces relaxation and focus
  • B vitamins (B6, B12): supports cognitive function


Thesis stands out as the best nootropics overall due to its balanced formula and flexibility to target energy, focus, and motivation. While the pricing may be higher, the personalized approach it provides justifies the cost if you know what you want to improve.

>>Check the best price for TakeThesis Nootropics

2. Noocube – Best Nootropics for Students


  • May help reduce stress of studying
  • Supports memory and cognition
  • Ideal for students and learners


  • May cause bloating for some

Who Is Noocube Best For?

Noocube is best if you’re looking to enhance your memory, making it an excellent choice for students, learners, and those seeking cognitive improvement in information processing and recall.

Noocube Benefits

Noocube’s key benefits lie in its ability to support memory, learning, focus, concentration, and overall cognitive function. It’s also stimulant-free and works great for sensitive users.


  • Two capsules daily
  • Best taken with breakfast


Noocube’s key ingredients include:

  • Bacopa monnieri: boosts memory formation
  • Huperzine A: aids information processing [2]
  • Alpha-GPC: enhances cognitive performance
  • Vitamin B1: supports brain health


Noocube offers a comprehensive solution for supporting cognition and memory boost. The different purchasing options (1 month, 3 months, 5 months supply) add flexibility if you prefer a different approach.

>>Check the best price for Noocube

3. Hunter Focus – Best Nootropics for Focus


  • Promotes sustained energy
  • Supports mental clarity, focus, and productivity
  • No energy crashes or jitters


  • Requires taking six capsules a day

Who Is Hunter Focus Best For?

Hunter Focus reviews recommend that it is best if you prioritize productivity and need focus that lasts throughout the day. Its blend of caffeine, L-theanine, and B vitamins offers a smooth energy boost with few drawbacks.

Hunter Focus Benefits

The primary benefits of Hunter Focus include enhanced productivity, improved focus, sustained energy, mental clarity, and alertness. It provides a reliable solution if you’re looking to stay productive without the usual energy crashes.


  • Six capsules daily


  • Caffeine: gives sustained energy
  • L-theanine: improves mental clarity [3]
  • B vitamins (B6, B12): boosts cognitive function
  • L-tyrosine: increases focus


Hunter Focus excels in providing a sustained energy boost without the drawbacks of traditional stimulants, making it a go-to choice if you’re seeking enhanced productivity and sustained energy.

>>Check the best price for Hunter Focus

4. Addall XR – Best Nootropics for ADHD Support


  • Contains GABA, Bacopa Monnieri, and B vitamins
  • Improves focus, attention, and decreases fogginess
  • Targeted solution for ADHD symptoms


  • Limited information on its ingredients

Who Is Addall XR Best For?

Addall XR is specifically designed for increased mental concentration, making it one of the best nootropics for ADHD. It’s best for improving focus and attention, but it’s important to consult a healthcare professional to discuss its potential in actually substituting prescription with over the counter adderall.

Addall XR Benefits

The primary benefits of Addall XR include improved attention and energy levels. It addresses the specific neurotransmitter imbalances and provides targeted support to keep you focused.


  • One or two capsules daily
  • Best taken in the morning


  • GABA: promotes focus and energy
  • Bacopa Monnieri: enhances memory and learning
  • Vitamins B1, B2, and B6: protects from oxidative stress [4]


Addall XR stands out as an effective solution if you’re looking for a quick boost to attention and focus, offering a natural substitute for Adderall.

>>Check the best deals for Addall XR

5. Mind Lab Pro – Best Daily Cognitive Boost


  • Premium blend of the best nootropics
  • Evidence-based dosing
  • Supports memory, focus, energy, mood, and brain health


  • May take time to see noticeable effects

Who Is Mind Lab Pro Best For?

Mind Lab Pro reviews say it is best for you if you’re seeking a supplement to take for everyday brain health. Its diverse blend of the best nootropics addresses various aspects of cognitive function, including memory, focus, energy, mood, and overall brain health.

Mind Lab Pro Benefits

Mind Lab Pro offers a wide range of cognitive benefits, including enhanced memory, improved focus, increased energy, and better mood. It provides students with a holistic solution for academic and cognitive challenges.


  • Take two capsules in the morning on an empty stomach
  • Two more around lunchtime if needed


  • Citicoline: improves memory [5]
  • Bacopa monnieri: boosts focus
  • Lion’s mane mushroom: supports brain health
  • Rhodiola rosea: elevates mood


Mind Lab Pro stands out as the best nootropics choice for a cognitive boost, offering a comprehensive blend of ingredients that support various cognitive functions.

>>Check the best deals for Mind Lab Pro

6. FOCL Day – Best Nootropics for Anxiety


  • Formulated with L-theanine, B vitamins, and lion’s mane mushroom
  • Suitable for daily use
  • Provides consistent cognitive support without harsh stimulants


  • May not offer as intense effects as some stimulant-based nootropics

Who Is FOCL Day Best For?

If anxiety’s been bothering you, FOCL Day could be just what you need. Packed with Lion’s mane, this nootropic supplement is a powerhouse for easing those anxiety symptoms—think less irritability, better sleep, and laser-sharp focus.

FOCL Day Benefits

It’s not just a supplement; it’s your daily brain booster and helps to sustain mental clarity. Think of FOCL Day as your cognitive cheerleader, rooting for your brain’s peak performance without shaking up your system with intense stimulants.


  • Take two capsules daily with a glass of water


  • L-theanine: induces relaxation
  • Vitamin B6: boosts cognitive function
  • Lion’s mane mushroom: enhances brain health [6]
  • Rhodiola rosea: improves mood [3]


FOCL Day is an excellent choice if you’re after daily cognitive support with antioxidants and without the intensity of stimulants.

>>Check the best deals for FOCL Day

7. Performance Lab Mind – Best Nootropics for Athletes


  • Includes branded ingredients Cognizin® and Sharp-PS®
  • Promotes concentration, information processing, and cognitive performance
  • Clean and minimalistic formula


  • Only available on their website
  • No vitamins–use it with a multivitamin or mineral supplement

Who Is Performance Lab Mind Best For?

For those in the fast lane—athletes and people who want to multitask—Performance Lab Mind is your co-pilot. It’s not just about the quick fix; it’s about fine-tuning your brain’s engine with premium fuel like Cognizin® citicoline and Sharp-PS® Green Phosphatidylserine.

Performance Lab Mind Benefits

The primary benefits of Performance Lab Mind include improved memory, enhanced focus, better concentration, and increased information processing.


  • Take one capsule daily


  • Cognizin® citicoline: improves memory [5]
  • Sharp-PS® Green Phosphatidylserine: enhances focus and concentration [7]


Performance Lab Mind reviews say the nootropic supplement caters to users looking for a specialized focus-enhancing nootropic, offering a minimalist, 1-2 punch approach to supporting brain health and overall cognitive function.

>>Check the best deals for Performance Lab Mind

8. Mind Vitality – Best Nootropic for Mental Fatigue


  • Contains adaptogenic herbs that combat/ease fatigue
  • Protects against stress and anxiety
  • Comprehensive support for mood and calmness


  • May not provide instant relief

Who Is Mind Vitality Best For?

Mind Vitality isn’t just a supplement; it’s the best nootropic supplement for those grappling with fatigue that hits you like a ton of bricks, both physically and mentally. If you’re looking to elevate your mental game and find that inner zen, Mind Vitality is the answer you’ve been searching for.

It’s not about just getting through the day; it’s about crushing it with a sense of calm that only comes from a well-nourished brain.

Mind Vitality Benefits

The primary benefits of Mind Vitality include stress and anxiety management, relaxation, improved mood, and overall calmness. It provides a holistic approach to mental well-being, making it an ideal choice if you’re after the best nootropics for natural stress relief.


  • Take three capsules daily


  • Ashwagandha: reduces stress [8]
  • Rhodiola rosea: improves mood [9]
  • L-theanine: induces relaxation
  • GABA: supports calmness
  • Magnesium: enhances focus


Mind Vitality stands out as an effective solution for stress and anxiety, providing comprehensive support for mood and relaxation. It offers an ayurvedic approach to stress relief and mental well-being.

>>Check the best deals for Mind Vitality

9. Neuro Gum – Best Nootropic Gum/Mint


  • Good for red blood cell and neurotransmitter production
  • Users love the peppermint and cinnamon flavors
  • Slow-release medium


  • Not stimulating

Who is Neuro Gum Best For?

Neuro Gum? It’s the best nootropic if you just can’t stand pills or don’t want to juggle dosages. Pop a piece and let the good vibes roll in as it turbocharges your brain gears.

Neuro Gum Benefits

Think of it as a personal trainer for your neurons. With caffeine and theanine in the mix, you’re not just alert, you’re ready to tackle anything with speed and precision. And let’s not forget Vitamin B6 — it’s like a backstage pass for serotonin, GABA, and dopamine, giving you that all-access feel-good experience [4].


Take two gum pieces or mints each day, either together or separately.


  • Caffeine: Boosts energy
  • L-theanine: helps reduce the effects of caffeine. Also enhances mood.
  • Vitamin B6: Supports neurotransmitter production
  • Vitamin B12: Improves alertness


Neuro Gum delivers a nootropic blend that’s as easy to take as your morning breath of fresh air. They help you have better focus for your everyday tasks.

>>Check the best deals for Neuro Gum

10. Brain Pill – Best Nootropics for Memory


  • May bolster brain cell health
  • Packed with antioxidants
  • Can crank up your dopamine and serotonin levels


  • If you’re on blood thinners, steer clear

Who is Brain Pill Best For?

For older adults, Brain Pill stands out as a top-tier nootropic, with ingredients that may protect your brain cells.

Brain Pill Benefits

Imagine Phosphatidylserine as your brain cells’ personal fitness trainer, and docosahexaenoic acid, or DHA, as the nutritious smoothie that helps them flex and recover. Together, they’re a dynamic duo, proven to sharpen the mind and brighten the moods of older adults [10].


Take two capsules of Brain Pill daily.


  • Bacopa monnieri: May support brain health, including memory
  • Citicoline: Enhances cognitive function
  • L-tyrosine: Improves alertness
  • Phosphatidylserine: Supports brain health
  • Vinpocetine: Enhances cerebral blood flow
  • Ginkgo biloba: Promotes brain health
  • DHA omega-3 complex: Supports brain development
  • L-theanine: Promotes relaxation
  • Huperzia serrata: Associated with memory enhancement
  • Vitamins B5, B6, B9, and B12: Essential for energy production


According to Brain Pill reviews, one should think of the supplement as the caretaker of your cerebral sanctuary, potentially offering long-term protection and keeping those neurons firing smoothly.

>>Check the best deals for Brain Pill

11. BetterBrand – Most Affordable Nootropics


  • BetterBrand may dial down stress hormones
  • Phosphatidylserine may enhance your focus
  • Less than a dollar a day.


  • Does not contain caffeine or B vitamins

Who is BetterBrand Best For?

If you’re watching your wallet but still want to join the nootropic revolution, BetterBrand is your go-to supplement. It’s perfect for nootropic newbies who aren’t ready to splash the cash just yet.

BetterBrand Benefits

BetterBrand’s adaptogens work to help you feel more relaxed in gummy form. They’re all about lowering stress and upping energy. And phosphatidylserine? It’s like a laser focus beam, helping you zero in on what matters. A study even showed that folks with ADHD dropped their DSM-IV scores and boosted attention by a whopping 90% after using it [11].


Just take one capsule of Better Brand every day.


  • Ashwagandha: May reduce stress and anxiety
  • Phosphatidylserine: Supports brain health
  • Pinus pinaster: May improve blood flow
  • Rhodiola rosea: Helps with stress adaptation
  • Schisandra: Improves mental performance


Don’t let the price fool you—BetterBrand punches well above its weight in the focus and brain health ring.

>>Check the best deals for BetterBrand

12. Earth & Star Mushroom Gummies – Best Stimulant-Free Nootropic Supplement


  • Brain boost without the buzz of caffeine
  • No intense enhancers, just pure, focused clarity
  • Customers love the raspberry flavor
  • A duo of ingredients keeps it simple yet effective


  • Not a complex formula

Who is Earth & Star Mushroom Gummies Best For?

If you’re already riding the stimulation wave from another source, Earth & Star Mushroom Gummies are your perfect nootropic sidekick. Ideal for stacking, these gummies keep it neat with just two key ingredients.

Earth & Star Mushroom Gummies Benefits

Lion’s mane isn’t just another mushroom; it’s a brain-boosting powerhouse, working hand-in-hand with L-theanine to ramp up your mental chemistry. Plus, it’s a cheerleader for nerve growth factor, keeping your neurons thriving [12].


Chew two mushroom gummies daily.


  • L-theanine: Increases focus
  • Lion’s mane: Stimulates brain cell growth


Gentle on the mind yet firm in support, Earth & Star Mushroom Gummies offer a no-caffeine, non-stimulating approach to brain health. It’s the mellow path to mental wellness.

>>Check the best deals for Earth & Star Mushroom Gummies

What Are Nootropics?

Nootropics, or “smart drugs,” are the brain’s allies in the modern world’s search for a brain boost. They’re a diverse arsenal, ranging from natural dietary supplements to pharmaceutical-grade weapons, all engineered to boost your mental prowess.

Dietary Supplements

The best nootropic supplements are packed with vitamins, minerals, and herbal extracts. They’re the over-the-counter alternatives, making cognitive support accessible to everyone.


Pharmaceutical nootropics are prescribed for conditions like ADHD. They’re potent, they’re powerful, and, unlike dietary supplements, they require supervision from a healthcare professional.

While the best nootropic supplements are your everyday cognitive support, pharmaceuticals are the more potent of the two and often prescribed when dietary supplements aren’t enough.

How Do Nootropics Work?

Nootropics are like the conductors of your brain’s symphony, orchestrating neurotransmitters such as dopamine, serotonin, and acetylcholine to enhance mental harmony:

  • Modulating Neurotransmitters: The best nootropics are the maestros, fine-tuning your brain’s chemical messengers to promote seamless cognitive performances.
  • Enhancing Cerebral Blood Flow: Some nootropics act like cerebral personal trainers, boosting brain circulation to ensure a steady flow of oxygen and nutrients.
  • Providing Neuroprotection: Many top-tier nootropics serve as the brain’s bodyguards, armed with antioxidant properties to shield your neurons from the onslaught of oxidative stress.

Common Nootropic Ingredients

Many of the best nootropic supplements have one or two common ingredients, such as:

  • Bacopa Monnieri
  • L-Theanine
  • Caffeine
  • Ashwagandha
  • Rhodiola Rosea
  • Choline
  • Phosphatidylserine
  • Lion’s Mane mushroom
  • L-Tyrosine
  • Huperzine
  • Alpha GPC

Benefits of Nootropics

The best nootropics are like a multi-tool for your mind, offering a suite of cognitive tools for every mental task.

  • Improved Memory: They’re the upgrade button for your memory, enhancing the recall of both yesterday’s details and last year’s memories.
  • Increased Focus and Concentration: The best nootropics sharpen your mental lens, bringing life’s details into crystal clear focus while sidelining distractions.
  • Stress Reduction: They’re the zen masters of the supplement world, helping your body to find its calm in the chaos.
  • Enhanced Creativity: The best nootropics unlock the gates to your creative pathways, inviting out-of-the-box thinking to play.
  • Mood Regulation: They’re the cheerleaders for your mood, fostering a positive and emotionally balanced state of mind.
  • Increased Mental Energy: Top nootropic supplements are the espresso shot for your brain, providing a sustainable jolt to your alertness and energy levels.

>>Check the best price for TakeThesis Nootropics

Potential Side Effects of Nootropics

While generally considered safe, some people may experience side effects, including:

  • Insomnia
  • Gastrointestinal discomfort
  • Headaches
  • Jitters or anxiety

Why Should You Take the Best Nootropics?

Nootropics are the secret sauce for those looking to add a little extra cognitive zest to their daily routine:

  • Cognitive Enhancement: Students and professionals alike reach for the best nootropics to turn their brain power up to eleven.
  • Stress Management: The best nootropics can be like a mental spa day, helping the body unwind and maintain emotional equilibrium.
  • Increased Productivity: Nootropics are the turbo button for those who want to get things done fast, enhancing mental energy for peak performance.
  • Mood Improvement: For those seeking a sunnier disposition, nootropics might just be the ray of light for a balanced emotional state.

Who Should (And Shouldn’t) Try Nootropics?

Nootropics can be beneficial for students, professionals, and people seeking cognitive enhancement. However, people with underlying health conditions, pregnant women, or those taking specific medications should consult with a healthcare professional before trying nootropics.

Where Can You Buy the Best Nootropics?

Nootropics are available from various sources, including official manufacturers’ websites, reputable online retailers, and select physical stores. Choosing reliable platforms is crucial as you want to ensure the quality and authenticity of the supplements.

Nootropics Cycling

Nootropics cycling involves alternating between periods of usage and non-usage to optimize effectiveness and minimize potential tolerance or dependence. Cycle lengths may vary, but a common approach is using nootropics for several weeks, followed by a break of equal length.

Not all products require cycling, so it’s important to read the manufacturer’s instructions carefully, focusing on the ingredients and your individual response.

>>Check the best price for TakeThesis Nootropics

How We Evaluated the Best Nootropics

When choosing the best nootropics, we want to make sure you know what to look for before buying. Here’s how we determined the ranking for the best nootropic supplements.

  • Effectiveness: We assessed the cognitive benefits provided by the best nootropics based on scientific research, user reviews, and expert opinions.
  • Safety: Safety considerations included potential side effects, interactions, and recommended dosages.
  • Cost: We analyzed the affordability and value for money that each nootropic offers, considering the price relative to the benefits provided.
  • Convenience: We considered factors such as dosage regimens and ease of incorporation into daily routines.

>>Check the best price for TakeThesis Nootropics

FAQs About the Best Nootropics

Still curious about the top nootropic supplements for 2024? Let’s dive into the most frequently asked questions and clear the air.

What Is the #1 Rated Nootropic?

The crown for the best nootropic is up for grabs, as it really hinges on what you’re after. TakeThesis is our champ as a well-balanced supplement, but your goals are key in deciding what nootropic to get.

Are Any Nootropics Worth It?

Value is in the eye of the beholder—or in this case, the brain of the beholder. Some may find nootropics to be the secret sauce to their success, while others might give them a shrug.

Is Adderall Considered a Nootropic?

Adderall might give you that mental edge, but it’s not in the nootropic family. It’s a prescription player, tackling ADHD with a doctor’s game plan.

How Do I Choose the Best Nootropics?

Picking the perfect nootropic is like choosing a personal brain coach. Consider your goals, do your homework on the ingredients, and maybe have a chat with a healthcare pro.

Do Nootropics Actually Work?

Nootropics can be like a gym for your brain, but not everyone’s lifting the same weights. Ingredients, dosages, and your unique brain chemistry play a big part.

Are Nootropics Safe?

Stick to the script—recommended dosages, that is—and nootropics are generally playing it safe. But bodies are unique, so keep that dialogue with your doc open.

What Should I Expect From a Nootropic?

Set your sights on the nootropic’s promises: sharper focus, better memory, or maybe a chill vibe.

How Do Nootropics Affect the Brain?

Nootropics get in there and mix it up with your neurotransmitters, boost brain blood flow, and act like a shield for your neurons.

Will Nootropics Make Me Smarter?

“Smarter” is a loaded word, but nootropics are here to support your brain’s hustle. Clarity, focus, memory; they’ve got your back.

Does Thesis Nootropics Actually Work?

Thesis could be your brain’s new best friend, according to the buzz from customers and experts. But as with any friendship, it’s all about chemistry.

Is Thesis Better Than Adderall?

Thesis and Adderall aren’t even running the same race. Thesis is all about that natural brain boost, while Adderall’s got a prescription pad behind it.

Best Nootropics 2024: Final Thoughts

Nootropics are your backstage pass to the brainpower show—memory, focus, mood—they’re all on the setlist. The best ones for you? They’re the ones that vibe with your personal goals and style. Nootropics like TakeThesis are like the headliner for mental clarity and performance.

Just remember, nootropics aren’t a magic act—they’re part of the whole healthy lifestyle gig.


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