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Instant Knockout Review

Instant Knockout Review

By Kire Stojkovski M.D
Editor Jonathan Hoarau Published 29 May 2023
Time to read 12 min

Are you suffering from stubborn body fat that just won’t melt away?
We’ve done our research and in our Instant Knockout review, we cover one of the most powerful appetite suppressants. Originally designed for MMA fighters and popularized by boxers like Diego Sanchez, Instant Knockout works to increase fat oxidation and build energy stores to keep your performance game strong.
Let’s dive into the research and the pros and cons behind this supplement.

What Is Instant Knockout?

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Instant Knockout is a fat burner supplement for body weight loss that’s made up of a proprietary blend of natural ingredients, including green tea.
These substances are combined to enable you to lose fat successfully, while maintaining the energy levels you need for building muscle and hitting your goals simultaneously. It won’t happen in an instant, but that doesn’t mean all is lost.
This dual purpose is what could make Instant Knockout a unique supplement, as otherwise, gaining muscle mass can be a near-impossible task when burning fat at the same time.

How Do You Use Instant Knockout Fat Burner?

Like many supplements, Instant Knockout works best when you take it each day, as instructed by the manufacturer, Roar Ambition.
You’ll take one Instant capsule, 4 times per day. More on this later in the review.

How Does Instant Knockout Work?

Instant Knockout contains 10 active ingredients for losing weight. The sources and benefits are described here in detail.
Ingredients in Instant Knockout include:

  • Vitamins B6 and B12
  • Piperine
  • Glucomannan00
  • Cayenne Pepper Seeds
  • Chromium
  • Green Tea Extract
  • Green Coffee Bean
  • Zinc
  • Caffeine Anhydrous

Vitamins B6 and B12

Vitamins B6 and B12 are just two of the essential B vitamins that play multiple roles in the body. For starters, both of them support communication between neurotransmitters, making them mood boosters and useful for clearing up a foggy brain.
Vitamin B6 in particular also helps with metabolism and B12 supports energy levels in the body, both are important aspects of burning fat and physical performance [1], [2].
B6 is found in various foods including starchy vegetables, fish, beef liver, tofu and a variety of nuts including almonds and pistachios. You’ll find B12 in similar food items, in addition to milk products, fortified breakfast cereals and grains.


Glucomannan comes from the fiber-heavy Konjac root of the Konjac plant, also known as the “devil’s tongue” or “snake palm”. You’ll find this plant in Eastern Asia and it’s long been used in both Japanese and Chinese medicines.
It may support better heart health and digestion, especially those who are constipated easily, which could promote fat burning and loss of weight [3].
Glucomannan may also help you feel full for a longer period of time, acting as an appetite suppressant. This aspect, in particular, is crucial where maintaining portion sizes is often a challenge for those looking to lose body fat.

Cayenne Pepper Seeds

Cayenne Pepper Seeds are full of vitamins and nutrients including Vitamin A, Manganese, Vitamin C, Vitamin E and more. These seeds come from the Cayenne Pepper plant, which belongs to the nightshade family, commonly found in Southwest America and Mexico, among other locations.
You’ll often find cayenne pepper or the extract in fat-burning pills due to their variety of benefits including metabolic support, suppression of appetite, boost in overall digestive health and pain relief, to name a few [4].
All of these factors may increase the fat burning capability in your body, without reducing your energy levels day to day.

Caffeine Anhydrous

Caffeine Anhydrous comes from a coffee plant and you’ll see it included in many weight loss supplements as it aids the body in maintaining a sense of alertness while limiting calories.
This type of caffeine, in particular, is dehydrated and concentrated to provide a strong dose. Athletes often use caffeine anhydrous to improve athletic performance, which indicates it’s a beneficial substance for physical endeavors while watching your body composition [5].
While caffeine itself won’t directly lead to burned fat, it can help decrease your cravings and provide the energy you need to build muscle in the process.

Green Tea Extract

Green Tea Extract is one of the most important ingredients in the Instant Knockout formula. The source of this extract is found in the Camellia Sinensis plant grown throughout Asia.
It’s a popular product for weight loss and due to the other purported benefits for the body including: antioxidant (fights against aging), antiviral and possible “chemopreventive” qualities, which means it may help fight against certain cancers [6].
Green tea extract may support fat burning by lowering blood fat levels, reducing appetite and boosting hormones that help break down fat, such as norepinephrine. This process helps the body release fat into the bloodstream, where it’s then consumed for energy.


Chromium is a naturally occurring mineral that helps the body turn food into energy, via insulin production. This might be particularly useful for those with insulin sensitivity or difficulties with metabolism.
It may help the body burn a higher amount of calories and reduce appetite because of this, enhancing the fat loss and muscle building process [7].
You can also find GTF Chromium in certain foods including broccoli, poultry, apples, bananas, whole grains, potatoes and more.


Zinc is another essential mineral included in Instant Knockout. It’s found in oysters, seafood, beans, nuts, fortified grains and more.
Zinc is known for boosting immunity, which is important when you’re following a strict exercise regime and diet plan, which can put stress on the body. It also plays a supportive role in the metabolic process, helping you break down food to be used for energy.
A deficiency in Zinc can lead to digestive issues and a slow metabolism, which indicates it may hinder anyone looking to burn fat successfully [8].


Piperine may be one of the lesser known ingredients on this list, though it’s source, black pepper, is known by just about everyone worldwide. It’s an alkaloid, or organic compound, that’s similar to the one found in Cayenne Pepper.
This warming spice promotes a healthy digestive system, which is an important component to avoiding inflammation, bloating and aiding in shedding weight.
Piperine may help break down fat cells, as well, increasing your chance at burning away stubborn fat [9].

Green Coffee Bean

Green Coffee Bean makes for the second caffeinated substance in Instant Knockout, indicating that Instant Knockout may be successful at boosting energy levels. It comes from coffee beans before they are roasted.
These beans contain an ingredient called “chlorogenic acid” which may have an antioxidant effect. This means it could help fight free radicals that come with the aging process.
This acid may also help manage blood pressure and aid in the weight loss process, though studies are inconclusive at this time [10].

What Are the Side Effects of Taking Instant Knockout?

Instant Knockout product contains substances that are mostly natural, which means these capsules are a safer, healthier option for every day use.
Still, as with any weight loss supplement, there could be unwanted side effects while consuming Instant Knockout.
This is particularly the case if you have any preexisting conditions that might be made worse by any of the ingredients, or combination of, listed above.
Possible deterrents include:

  • Sweating more than usual
  • Headache
  • Upset stomach
  • Diarrhea
  • Insomnia
  • Difficulty swallowing (the capsules are large)
  • Nervousness or anxiety
  • Difficulty concentrating
  • Irritability
  • High blood pressure
  • Rapid heart rate

Are you concerned about any of the consequences listed above?
For those that are sensitive, you can take a lower dose of the Instant Knockout supplement to start with, as your body adjusts. Do keep in mind that these pills in and of themselves, aren’t dangerous, so long as you take them as advised.

What Is the Safest Rate of Weight Loss?

The rate of losing weight is a highly contested topic in the world of nutrition and bodybuilding. As we know, weight loss does put stress on the body each day, which could possibly lead to a compromised immune system, among other side effects.
To avoid any complications, especially if you’re taking fat burners, you want to lose weight at a safe rate. This is specifically the case for those that are looking to build muscle at the same time, as you’ll need the energy to keep up.
According to many doctors and professionals, losing 1 to 2 pounds per week is deemed satisfactory, while losing more during that time period could be potentially dangerous.
Rapid weight loss could cause:

  • Hair loss
  • Muscle loss
  • Irritability
  • Fatigue
  • Nutritional deficiencies
  • Constipation
  • Mental fog
  • Dizziness
  • Menstrual irregularities

Avoid these symptoms by using a balanced approach to fat burning, versus a more intense regime that could lead to illness and frustration.

How Should I Take Instant Knockout?

Roar Ambition, the manufacturer of the Instant Knockout product, lays out transparent guidelines for making the most of the Instant Knockout supplements. You’ll find these on the company’s official website.
The recommended schedule is as follows, including four Instant Knockout capsules, per one day. Each capsule should be consumed with a large glass of water:

  • First capsule: Before breakfast, upon waking up
  • Second capsule: Between breakfast and lunch times
  • Third capsule: One hour after lunch
  • Fourth capsule: One hour before dinner

It may take around one month or 30 days for the Knockout capsules to take effect, so do keep track of your losses and gains accordingly.

What If I Miss a Dose of Instant Knockout?

Due to the possible side effects around consuming too much caffeine and fat burners at large, we don’t recommend doubling up on your supplements or this Instant Knockout product if you happen to miss a dose.
Furthermore, the body can only absorb so much of any one vitamin or mineral at a time, which means taking a double dose of Instant Knockout could prove ineffective and wasteful.
Instead, play it safe and catch your next Instant Knockout dose accordingly, whether later in the evening or the next day.

Can I Take More for Faster Results?

Well, Instant Knockout doesn’t work that way and you’ll want to avoid taking a 1 month supply in a shorter time frame.
Not only could this cause unwanted side effects or be ineffective, it could lead to burnout, fast. The company, along with health professionals and doctors, will tell you that relying on a supplement alone to burn fat won’t work.
Instead, take Instant Knockout by pairing it with a well-balanced diet and exercise regime.
Other factors that may help promote fat loss and muscle growth, alongside Instant Knockout supplementation, include:

  • Consistent sleep schedule (at least 8 hours per night)
  • Low consumption of alcohol
  • Keeping stress levels in check
  • Low sugar intake

Where Is Instant Knockout Manufactured?

The Instant Knockout supplement is manufactured in certified GMP and FDA-approved facilities, indicating a high standard of production is maintained. The Roar Ambition facilities are located in Tennessee, Australia, UK, Europe and Canada.
Aside from Instant Knockout, this manufacturer also produces the following supplements for pre workouts, the best fat burners to burn more calories, testosterone boosters and nootropics for focus:

  • Hunter Focus
  • Hunter Burn
  • Hourglass Fit
  • 4 Gauge
  • Prime Male
  • TestoFuel
  • Hunter Test

According to the Knockout official website, you’ll get free delivery on purchases made totaling above $100. If you buy 3 bottles, you’ll get 1 free bottle.
If you’re unhappy with the Knockout product for any reason, take advantage of the money back guarantee within 90 days of your purchase.

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Instant Knockout Review in Conclusion

Made with MMA fighters in mind, the Instant Knockout fat burner is manufactured by the well-known Roar Ambition company. Home to many top-of-the-line supplements, Instant Knockout is one of many day to day products on offer.
In this review, we found that you may be able to lose weight safely, as the body burns more calories and increases your metabolic rate, while you feel fuller day to day. Instant Knockout contains natural ingredients to support you, like green tea extract and vitamin B12 for a boost in energy. You’ll get two versions of caffeine here.
Make sure to take Instant Knockout as instructed for the best results and always consult a doctor should you have any questions or experience unwanted side effects from a fat burner.
Taking Instant Knockout may help you in your fat-burning mission, so long as you do it safely and responsibly. Remember, if you buy 3 bottles, you’ll get a 1 month supply for free. Not satisfied? Use the money back guarantee within the 90 day window to get a refund.

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2. Ryan-Harshman, Milly, and Walid Aldoori. “Vitamin B12 and Health.” Canadian Family Physician Medecin De Famille Canadien, College of Family Physicians of Canada, Apr. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2294088/.

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6. “NCI Drug Dictionary.” National Cancer Institute, www.cancer.gov/publications/dictionaries/cancer-drug/def/green-tea-extract.

7. Anton SD;Morrison CD;Cefalu WT;Martin CK;Coulon S;Geiselman P;Han H;White CL;Williamson DA; “Effects of Chromium Picolinate on Food Intake and Satiety.” Diabetes Technology & Therapeutics, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/18715218/.

8. CI. Gamboa-Gomez, NE. Rocha-Guzman, et al. “Zinc Supplementation Improves Body Weight Management, Inflammatory Biomarkers and Insulin Resistance in Individuals with Obesity: a Randomized, Placebo-Controlled, Double-Blind Trial.” Diabetology & Metabolic Syndrome, BioMed Central, 1 Jan. 1970, dmsjournal.biomedcentral.com/articles/10.1186/s13098-019-0497-8.

9. Shah, Shreya S, et al. “Effect of Piperine in the Regulation of Obesity-Induced Dyslipidemia in High-Fat Diet Rats.” Indian Journal of Pharmacology, Medknow Publications, May 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3113382/.

10. Onakpoya, Igho, et al. “The Use of Green Coffee Extract as a Weight Loss Supplement: a Systematic Review and Meta-Analysis of Randomised Clinical Trials.” Gastroenterology Research and Practice, Hindawi Publishing Corporation, 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC2943088/.