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Adderall and Energy Drinks | A Dangerous Combination or Safe in Moderation?

Adderall and Energy Drinks | A Dangerous Combination or Safe in Moderation?

By Kire Stojkovski M.D
Editor Jonathan Hoarau Published 15 May 2023
Time to read 12 min

It’s one of those nights: you’ve got to start early and possibly pull an all-nighter. As you reach for another can of energy drink, you pause, wondering whether it might interact with your Adderall medication.

Yes, it will! Combining these two stimulants might seem like a good idea to power through, but in reality, it’s a risky combination. Our article delves into why pairing Adderall and energy drinks can be harmful and explores natural alternatives, like MindVitality, for a low-risk mental boost.

Adderall and Energy Drinks: How Do They Work?

  • Adderall is a stimulating substance commonly prescribed for treating ADHD but used for other sleep disorders.
  • Energy drinks are full of caffeine, a natural drug that stimulates the brain and nervous system and is found in food, beverages, and some medications.
  • Adderall and caffeine have similar adverse effects, including headaches, insomnia, mood changes, and high blood pressure.
  • Caffeine increases the effectiveness of amphetamines like Adderall, making the user feel a stronger impact and increasing the negative side effects leading to a possible medical emergency.
  • People taking high doses of Adderall and energy drinks may experience severe psychological and physical dependence that can intensify unpleasant side effects.

Check the best price for the natural Adderall substitute MindVitality

Adderall and Drinks 2

What Is Adderall?

Adderall is a brand-name prescription drug approved by the Food and Drug Administration and contains a combination of amphetamine and dextroamphetamine, a central nervous system stimulant. This mixture of amphetamine salts affects chemicals in the brain that contribute to impulse control and hyperactivity [1].

What Does Adderall Do?

So, how does Adderall work, and what does it do? Adderall increases the level of several neurotransmitters, including dopamine, which plays a direct role in how we receive pleasure as well as how we think, plan, and focus [2]. It’s also the reason we find certain things interesting.

Drugs like Adderall can produce the following symptoms on the body and mind:

  • Higher energy levels
  • Improved focus
  • Decreased restlessness and fidgeting
  • Increased alertness
  • Longer attention span
  • Rapid heartbeat
  • Higher blood pressure

What Is Adderall Used For?

Doctors prescribe Adderall for the treatment of ADHD, which can improve focus and concentration by reducing hyperactivity and improving attention span. Because Adderall produces an excess amount of dopamine, this treatment affects even those who do not have ADHD and can create feelings of euphoria and increase energy levels [3].

This prescription drug treatment is also used for the sleep disorder narcolepsy and aids in boosting levels of a brain chemical called norepinephrine. This stimulant helps those with narcolepsy stay awake during the day and promotes general wakefulness [4].

Mood effect of adderall
Adderall increased the PA score significantly more than the placebo

What Is Caffeine?

Caffeine is a natural substance found in the leaves and fruits of over 60 plant species, including coffee beans, kola nuts, and tea leaves. It’s the world’s most commonly used psychoactive drug [5].

Caffeine is found in everything from beverages like soda and caffeinated coffee, food such as chocolate and energy bars, and some non-prescription medications and supplements like caffeine pills.

What Does Caffeine Do to the Body?

As a stimulant, caffeine consumption increases activity in the nervous system, helping you stay awake and preventing tiredness. It can also increase the circulation of chemicals such as adrenaline and cortisol [6].

Some of the effects of caffeine on the body and mind include:

  • Increased breathing and heart rate
  • More physical energy
  • High blood pressure
  • Uneven heart rhythm
  • Increased mental alertness

Caffeine also acts as a diuretic, causing you to urinate more, which helps get rid of extra water and salt in the body [7]. It can increase the release of stomach acid, leading to digestive issues like heartburn and upset stomach [8]. There’s also the possibility of caffeine interfering with the absorption of calcium in the body [9].

Check the best price for the natural Adderall substitute MindVitality

Adderall and Energy Drinks: Side Effects

Even though Adderall and energy drinks or caffeine supplements are very different substances, they are both stimulant drugs and affect the body in similar ways with a number of negative effects.

Caffeine Side Effects

For most people, caffeine products, like energy drinks, are non-harmful stimulants as long as you follow the recommended dose of 400mg (about two cups a day) [10]. However, if your caffeine intake is much higher, you may experience a high risk of negative symptoms such as:

  • Restlessness
  • Insomnia
  • Shakiness
  • Headaches
  • Heart palpitations
  • Dizziness
  • Anxiety
  • Dehydration
  • Dependency

Adderall Side Effects

Being a powerful prescription drug, Adderall has far more side effects than caffeine, energy drinks, or other stimulants. It may negatively affect people even when taken as directed for the treatment of ADHD. These effects increase if this drug is taken in toxic doses and may include the following symptoms:

  • Restlessness
  • Increased heart rate, palpitations, and blood pressure
  • Mood swings (irritability, excitability, agitation)
  • Headaches
  • Dry mouth
  • Dizziness
  • Fear and anxiety
  • Insomnia or inability to stay asleep
  • Digestive issues (constipation, upset stomach, diarrhea, etc.)
  • Loss of appetite and weight loss
  • Blurry vision
  • Hair loss
  • Sexual problems (decreased sex drive, impotence)
  • Addiction and dependency

Check the best price for the natural Adderall substitute MindVitality

Can You Mix Adderall and Energy Drinks?

It’s possible for the body to have a negative reaction when taking Adderall and energy drinks, but this can vary from person to person. In general, it’s advised to avoid combining these two stimulant drugs as the symptoms and side effects of Adderall may become more intense if also consuming caffeine [11].

Are There Health Risks of Adderall and Energy Drinks?

That depends. A minor caffeine intake, such as a chocolate bar or a cup of coffee mixed with Adderall, is generally safe. Unfortunately, some people seek a more heightened effect by taking high doses of these drugs. This is not advised and can be dangerous, leading to a possible Adderall overdose.

Mixing Adderall and energy drinks may affect the following:

Adderall and Drinks 3

  • Sleeping Patterns – Both Adderall and energy drinks can increase attention and alertness. When taken together, the effects of these two substances can make it difficult for you to fall asleep and may lead to insomnia [12].
  • Mood – Adderall and energy drinks have similar side effects on the central nervous system that may affect mood. If taken together, this can intensify feelings of nervousness, anxiety, and aggression [13].
  • Heart and blood pressure – The chemical substances in Adderall are similar to caffeine as they can cause the blood vessels to constrict. Combining these two could raise your heart rate and bring your blood pressure to dangerous levels [14].
  • Addiction and dependency – When Adderall treatment is abused and enhanced by caffeine use, there’s a greater chance of caffeine dependence and Adderall addiction. Withdrawal symptoms, like headaches and fatigue, become stronger between doses and are common with this kind of substance abuse [15].

Does Caffeine Make Adderall Less Effective?

Products with caffeine, like coffee, tea, and energy drinks, may reduce the effectiveness of Adderall treatment. Caffeine is a diuretic and aids in the body’s release of water and salt, which could shorten the effects of Adderall by pushing the drug out of the body faster [16].

Check the best price for the natural Adderall substitute MindVitality

Adderall vs. Nootropics

Are you looking for natural Adderall alternatives? A nootropic is a natural supplement or drug compound that enhances mental function, including concentration, motivation, and attention. It does this by increasing and improving the blood supply and circulation to the brain [17]. They also improve memory by protecting cells from inflammation.

Some nootropics include natural ingredients like ginkgo biloba, ginseng, and creatine. Still, some manufacturers combine a variety of nootropics to make a more potent supplement that can be in the form of pills, powders, and beverages. Because these are natural supplements, they are safe to take with other caffeinated foods, beverages, and other products.

The most significant difference between nootropics and Adderall is that nootropics do not require a prescription. However, nootropics are not regulated by the Food and Drug Administration like other medications [18]. Your local healthcare professional can provide medical advice on the best nootropics for your lifestyle goals.

Is It Safe To Use Adderall as a Study Pill?

Many students use Adderall and energy drinks for academic purposes to stay awake, alert, and focused for classes and exams. However, Adderall was not made as a study pill, and students who use these drugs for this purpose are prone to Adderall abuse and addiction.

Adderall will eventually wear off, leading to a withdrawal period that may cause depression, restlessness, and anxiety [19]. Overusing the drug can also lead to high Adderall tolerance, meaning that you need more of the drug in higher doses to attain the desired effects.

Eventually, Adderall treatment will lose its effectiveness in helping you study and may lead to an addiction.

Check the best price for the natural Adderall substitute MindVitality

Adderall and Energy Drinks: Best Nootropic Alternatives

Suppose you’re in the market to find something that will give you the benefits of Adderall treatment without the negative side effects. In that case, nootropic alternatives will provide the same mental boost and motivation. Here are our top picks for the best nootropic alternative.


Mind Vitality

MindVitality is a dietary supplement designed to boost mental energy and productivity throughout the day. It aims to improve various cognitive aspects such as focus, concentration, and fighting procrastination while also preventing fatigue during the mid-day slump.

MindVitality is formulated with natural ingredients like Ashwagandha, Rhodiola Rosea, and Korean Ginseng, among others, which are known to have cognitive-enhancing properties. Some of the benefits include reduced stress, increased focus, and mental sharpness.

MindVitality vs. Adderall

  • Effectiveness: Both MindVitality and Adderall serve different purposes. MindVitality is for anyone looking to enhance their cognitive functions and mental energy, whereas Adderall is specifically prescribed for individuals with ADHD or narcolepsy.
  • Safety: MindVitality is marketed as a safe supplement with natural ingredients and no side effects​​. Adderall, however, is associated with several serious side effects, including hypertension, fast heartbeat, insomnia, appetite suppression, and, in severe cases, overdose, sudden cardiac death, and stroke, among others​​.
  • Accessibility: MindVitality can be purchased over the counter, while Adderall requires a prescription from a healthcare provider due to its potential for abuse and serious side effects.

Check the best price for the natural Adderall substitute MindVitality

Addall XR

Addall XR

Addall XR is marketed as a brain health supplement designed to enhance focus, concentration, and energy. The brand is portrayed as vibrant and energetic, with its marketing suggesting an alternative to coffee or energy drinks despite caffeine being one of its main ingredients​.

Addall XR contains a proprietary blend that includes caffeine, gamma-aminobutyric acid (GABA), Bacopa Monnieri, and vitamins B1, B2, and B6​​.

Addall XR vs. Adderall

  • Benefits: While Addall XR is promoted as a general cognitive enhancer, Adderall is specifically formulated to manage ADHD symptoms and narcolepsy.
  • Efficacy and safety: The efficacy and safety of Addall XR have not been thoroughly established through clinical trials, unlike Adderall, which has undergone rigorous testing and is regulated by health authorities.

Check the best price for the natural Adderall substitute Addall XR



NooCube is considered one of the best nootropic stacks on the market for cognitive enhancement. It is an all-in-one mix, meaning all you need to do is take one supplement rather than many to get all of the cognitive function improvements.

NooCube was created with only natural ingredients, free of caffeine, by neuroscientists. They combined the most effective ingredients to help improve memory recall, balance mood, reduce anxiety, and increase motivation.

NooCube vs. Adderall

  • Natural: NooCube only contains natural ingredients to provide a boost in concentration and relaxation and may slow the process of aging in the brain. Adderall, though, contains amphetamine salts and is considered a medical-grade product.
  • Dosage: Patients prescribed Adderall may be instructed to take anywhere from 5mg to 40mg a day to reach the desired effect. That’s a pill every 4 or 5 hours as needed. NooCube’s dosage is simple: take two supplements in the morning with water.
  • Side Effects: Adderall is a powerful drug with many side effects that can possibly lead to addiction. As an all-natural supplement, NooCube has very few side effects. On rare occasions, some users have reported dizziness, stomach pain, headaches, and confusion.

Check the best price for the natural Adderall substitute NooCube

Adderall and Energy Drinks: FAQ

We scoured the internet to make sure we answered all of your questions about Adderall and energy drinks. Here’s what most people are asking.

How Should Adderall Make You Feel?

Some people claim a feeling of being high or euphoric while on Adderall. However, if taking this drug as prescribed, you typically only experience feelings of being energetic, self-confident, excited, and focused.

Adderall abuse may lead to manic and sometimes psychotic symptoms such as delusional thinking and hallucinations linked to an Adderall overdose. There’s also the possibility of panic attacks, anxiety, and paranoia.

Does Adderall Help With Anxiety?

The answer to does Adderall help with anxiety or depression is no. Adderall is a prescription drug only used to treat attention deficit hyperactivity disorder and narcolepsy. In fact, some symptoms of Adderall can intensify unpleasant side effects like depression and anxiety.

Does Adderall Help With Motivation?

Yes. Adderall is one of many prescription stimulants used to increase dopamine, a neurotransmitter associated with attention, pleasure, and motivation. Adderall is designed to increase your cognitive motivation. 

The benefits of performing a task are elevated, and the feeling of motivation makes you want to achieve your desired goals. You may try some of the Adderall alternatives we reviewed earlier if you need nootropics for motivation.

Can Caffeine Make ADHD Worse?

Yes. ADHD can cause insomnia and anxiety, which are also side effects of consuming caffeine and caffeinated products. The less sleep you have, the more cognitive issues may arise in someone with ADHD and can increase the very symptoms they’re trying to combat, such as focus and forgetfulness.

Adderall and Energy Drinks: Conclusion

Adderall is a central nervous system stimulant containing amphetamine and is only prescribed for ADHD and narcolepsy. Energy drinks contain caffeine, the most widely consumed drug found in nature. It is also a stimulant used in many foods, beverages, over-the-counter medications, and prescription drugs.

When consumed, even in moderate amounts, the effects of Adderall and energy drinks can be magnified, posing a severe health risk and the possibility of dependence, addiction, and drug abuse.

Fortunately, for those looking for that extra brain boost, natural nootropics, like MindVitality, provide the same positive effects without adverse reactions to other stimulants.

If you take Adderall for ADHD or narcolepsy and suffer from drug abuse or other substance abuse, contact your healthcare provider, who can provide medical advice on your best options.

Check the best price for the natural Adderall substitute MindVitality


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